Levels of evidence and meta -analysis

The term “evidence -based medicine” was first introduced by Gordon Guyatt of McMaster University in 1991. In 1996, Sackett et al. provided a widely accepted definition of EBM in the British Medical Magazine as “the conscientious, explicit and judicious use of the best current evidence to make decisions about the care of individual patients.” This definition highlighted the integration of clinical experience with systematic research to improve patient care. [3].

Since then, EBM has become the cornerstone of clinical practice guidelines, offering recommendations to diagnose and administer various disease -based diseases rigorously evaluated.

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